Population Genetics and Microevolutionary Theory

Population Genetics and Microevolutionary Theory

Templeton, Alan R.

John Wiley and Sons Ltd

06/2021

768

Dura

Inglês

9781118504239

15 a 20 dias

1730

Descrição não disponível.
Preface to the 2nd Edition ix

Chapter 1. The Scope and Basic Premises of Population Genetics 1-1

Basic Premises of Population Genetics 1-1

Population Genomics1-12

Section 1: Population Structure and History

Chapter 2. Modeling Evolution and the Hardy-Weinberg Law 2-1

How to Model Microevolution 2-1

The Hardy-Weinberg Model 2-4

Hardy-Weinberg for Two Loci2-19

Chapter 3. Systems of Mating 3-1

Inbreeding 3-1

Assortative Mating3-25

Disassortative Mating3-45

Chapter 4. Genetic Drift 4-1

Basic Evolutionary Properties of Genetic Drift 4-2

Founder and Bottleneck Effects 4-7

Genetic Drift and Disequilibrium4-11

Genetic Drfit, Disequilibrium, and System of Mating4-13

Effective Population Size4-18

Chapter 5. Genetic Drift in Large Populations and Coalescence 5-1

Newly Arisen Mutations 5-1

Neutral Alleles 5-3

The Coalescent5-22

Chapter 6. Gene Flow and Population Subdivision 6-1

Gene Flow Between Two Local Populations 6-1

The Balance of Gene Flow and Drift 6-6

An Example of the Balance of Drift and Gene Flow6-27

Factors Influencing The Amount and Patter of Gene Flow6-42

Total Effective Population Size in Subdivided Populations6-62

Multiple Modes of Inheritance and Population Structure6-71

Admixture6-76

Identifying Subpopulations and Population Structure6-81

A Final Warning6-96

Chapter 7. Population History 7-1

Inferring Historical Effective Population Sizes 7-6

Inferring Historical Gene Flow Patterns and Admixture 7-11

Using Haplotype Trees to Study Population History 7-19

Model Based Approaches to Phylogeographic Analysis 7-56

Direct Studies Over Space and Past Times 7-70

Historical Population Genetics and Macroevolution 7-75

Section 2: Genotype and Phenotype

Chapter 8. Basic Quantitative Genetic Definitions and Theory 8-1

"Simple" Mendelian Phenotypes 8-2

Nature Versus Nurture? 8-7

The Fisherian Model of Quantitative Genetics8-13

Chapter 9. Quantitative Genetics: Unmeasured Genotypes 9-1

Correlation Between Relatives 9-2

The Distinction Between Heritability and Inheritance9-17

Response to Selection9-19

The Problem of Between-Population Differences in Mean

Phenotype 9-21

Controlled Crosses for the Analysis of Between Population

Differences 9-30

The Balance Between Mutation, Drift, and Gene Flow Upon

Phenotypic Variance 9-36

Chapter 10. Quantitative Genetics: Measured Genotypes 10-1

Marker Association Studies 10-5

Candidate Loci10-35

Candidate Loci and Genetic Architecture10-51

Section 3: Natural Selection and Adaptation

Chapter 11. Natural Selection 11-1

The Fundamental Equation of Natural Selection: Measured

Genotypes 11-4

Sickle-Cell Anemia as an Example of Natural Selection 11-10

Adaptation as a Polygenic Process 11-24

The Fundamental Theorem of Natural Selection: Unmeasured

Genotypes 11-29

Some Implications of the Fundamental Equations of Natural

Selection 11-33

The Course of Adaptation and Natural Selection 11-47

Chapter 12. Interactions of Natural Selection with Other Evolutionary Forces

and the Detection of Natural Selection 12-1

The Interaction of Natural Selection with Mutation 12-3

The Interaction of Natural Selection with Mutation and System of

Mating 12-8

The Interaction of Natural Selection with Gene Flow 12-12

The Interaction of Natural Selection with Genetic Drift 12-21

The Interactions of Natural Selection, Genetic Drift, and

Gene Flow 12-28

The Interactions of Natural Selection, Genetic Drift, and Mutation 12-45

The Interactions of Natural Selection, Genetic Drift, Mutation, and

Recombination 12-65

Candidate Loci 12-71

Quantitative Genetic Approaches to Detecting Selection 12-75

The Neutralist/Selectionist Debate 12-80

Chapter 13. Units and Targets of Selection 13-1

The Unit of Selection 13-4

Targets of Selection Below the Level of the Individual 13-18

Targets of Selection Above the Level of the Individual 13-51

Chapter 14. Selection in Heterogeneous Environments 14-1

Coarse-Grained Spatial Heterogeneity 14-4

Coarse-Grained Temporal Heterogeneity 14-34

Fine-Grained Heterogeneity 14-56

Coevolution 14-74

Chapter 15. Selection in Age-Structured Populations 15-1

Life History and Fitness 15-3

The Evolution of Senescence 15-13

Abnormal Abdomen: An Example of Selection in an

Age-Structured Population 15-24

Overview 15-63

Appendices

Appendix 1. Genetic Survey Techniques A1-1

Appendix 2. Probability and Statistics A2-1

References R-1

Index
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